Grafodatskiĭ A S, Ternovskaia Iu G, Ternovskiĭ D V, Radzhabli S I
Genetika. 1978;14(1):68-71.
Karyotypes of two ferret species, Putorius eversmanni (2n = 38) and P. putorius (2n = 40), differ in a single Robertsonian rearrangement, resulting in decreased chromosome number in P. eversmanni. Interspecific hybrids from crosses between P. eversmanni and domesticated albino ferret P. putorius furo are fertile. Hybrid individuals have a chromosome set 2 = 39. Analysis of offspring from crosses of these hybrids showed that albinism is a recessive character. Offspring obtained from crosses between interspecific hybrid ferrets and between these hybrids and parental species was subjected to chromosome analysis. A statistically significant correlation was observed between the chromosome number and albinism. As a rule, albino hybrids have a chromosome number 2n = 40. This suggests that the locus, controlling albinism, is located at one of the two pairs of acrocentric chromsomes involved in Robertsonian rearrangement. The rare occurrence of albino hybrids with 2n = 39 may be attributed to recombination. According to our data, recombination probability is less than 0.5 which indicates that the albinism locus located near the centromere. Possible extrapolation of the data obtained for ferrets to other Mustelidae is discussed.
两种雪貂，艾氏鼬（2n = 38）和林鼬（2n = 40）的核型仅在一次罗伯逊重排上存在差异，这导致艾氏鼬的染色体数目减少。艾氏鼬与家养白化雪貂林鼬杂交产生的种间杂种是可育的。杂种个体的染色体组为2n = 39。对这些杂种杂交后代的分析表明，白化病是隐性性状。对种间杂种雪貂之间以及这些杂种与亲本物种之间杂交所获得的后代进行了染色体分析。观察到染色体数目与白化病之间存在统计学上的显著相关性。通常，白化杂种的染色体数目为2n = 40。这表明控制白化病的基因座位于参与罗伯逊重排的两对近端着丝粒染色体中的一对上。2n = 39的白化杂种罕见可能归因于重组。根据我们的数据，重组概率小于0.5，这表明白化病基因座位于着丝粒附近。文中还讨论了将雪貂获得的数据外推到其他鼬科动物的可能性。
