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促肾上腺皮质激素给药下大鼠肾上腺血管铸型的扫描电子显微镜观察,重点关注髓质动脉。

Scanning electron microscopy of corrosion cast of rat adrenal vasculatures with emphasis on medullary artery under ACTH administration.

作者信息

Nakamura K, Masuda T

出版信息

Tohoku J Exp Med. 1981 Jun;134(2):203-13. doi: 10.1620/tjem.134.203.

DOI:10.1620/tjem.134.203
PMID:6274058
Abstract

In the vascular system of the adrenal, the medullary artery is considered to be a shunt which controls cortical function by changing its diameter. To confirm this hypothesis, the medullary arteries of ACTH-treated and control rats were observed by scanning electron microscopy of methacrylate corrosion casts of blood vessels. After ACTH treatment, the medullary arteries were constricted mostly at their distal segments and sometimes also at other portions. This constriction probably results in an effective augmentation of adrenocortical blood flow. The diameter of capillaries in the glomerular zone and medullary sinusoids was markedly increased by ACTH. Small protrusions o the corrosion casts which supposedly corresponded to capillary fenestrations became prominent after ACTH administration in the fascicular and reticular zones.

摘要

在肾上腺的血管系统中,髓质动脉被认为是一种分流血管,它通过改变自身直径来控制皮质功能。为了证实这一假说,通过对血管甲基丙烯酸酯腐蚀铸型进行扫描电子显微镜观察,对促肾上腺皮质激素(ACTH)处理组和对照组大鼠的髓质动脉进行了研究。ACTH处理后,髓质动脉大多在其远端节段发生收缩,有时在其他部位也会收缩。这种收缩可能会有效增加肾上腺皮质的血流量。ACTH可使球状带和髓质血窦中的毛细血管直径显著增加。在束状带和网状带给予ACTH后,腐蚀铸型上那些据推测对应于毛细血管窗孔的小突起变得更加明显。

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