Tatarov G, Khristov S, Martinov S, Gergov P, Khristova V
Vet Med Nauki. 1981;18(4):3-9.
Attempts were made to produce inactivated vaccines against horse Herpes virus 1, using various inactivating agents and adjuvants, Best results were obtained with vaccine No 3 (glutaraldehide inactivator and "CTC" adjuvant). Used were two strains of the virus (St. Karaja and Varna). isolated in this country in cell cultures of a sucking pig kidney. Vaccine No 3 showed good immunogenic properties. Its application resulted in the full cease of abortions and respiratory diseases on the base of infection with the horse Herpes virus 1. The vaccination protects newborn colts from rhinopneumonitis if reimmunization of mares is carried out in the 6th-7th month of pregnancy.
人们尝试使用各种灭活剂和佐剂来生产抗马疱疹病毒1的灭活疫苗。使用疫苗3（戊二醛灭活剂和“CTC”佐剂）获得了最佳效果。使用了两种病毒株（圣卡拉亚株和瓦尔纳株），它们是在该国从吮乳仔猪肾细胞培养物中分离出来的。疫苗3显示出良好的免疫原性。其应用使基于马疱疹病毒1感染的流产和呼吸道疾病完全停止。如果在怀孕的第6至7个月对母马进行再次免疫，这种疫苗接种可保护新生马驹免受鼻肺炎的侵害。
