Metzger R A, Mulhern C B, Arger P H, Coleman B G, Epstein D M, Gefter W B
J Comput Assist Tomogr. 1981 Dec;5(6):830-3. doi: 10.1097/00004728-198112000-00008.
The therapy and prognosis of bronchioloalveolar carcinoma vary greatly with the solitary versus the diffuse form of the disease. Solitary disease demonstrates a high resectability rate with good long term prognosis. This contrasts with the rapidly fatal course associated with the diffuse form. To date, categorization of patients into either the solitary or the diffuse form has been based solely on conventional radiography. Multiple authors have reported cases of disease not demonstrated radiographically but discovered at surgery or autopsy. With the superiority of chest computed tomography (CT) for demonstrating parenchymal abnormalities, we propose that preoperative CT may be crucial in the workup of patients with presumed solitary bronchioloalveolar cell carcinoma. Early identification of diffuse disease or confirmation of the presence of solitary disease by CT may allow the institution of proper therapy and better evaluation of patient prognosis.
细支气管肺泡癌的治疗和预后因疾病的孤立型与弥漫型而有很大差异。孤立型疾病显示出高切除率和良好的长期预后。这与弥漫型相关的快速致命病程形成对比。迄今为止，将患者分类为孤立型或弥漫型仅仅基于传统的放射学检查。多位作者报告了在放射学检查中未显示但在手术或尸检时发现的病例。鉴于胸部计算机断层扫描（CT）在显示实质异常方面的优越性，我们提出术前CT对于疑似孤立性细支气管肺泡癌患者的检查可能至关重要。通过CT早期识别弥漫性疾病或确认孤立性疾病的存在，可能有助于采取适当的治疗措施并更好地评估患者预后。
