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[局限性进行性脂肪萎缩。一例新病例报告(作者译)]

[Partial progressive lipoatrophy. A new case-report (author's transl)].

作者信息

Moinade S, Thieblot P, Laurens D, Lambert M, Cailleba A

出版信息

Sem Hop. 1982 Jan 7;58(1):45-9.

PMID:6275548
Abstract

A new case of lipoatrophic diabetes with some peculiar features is reported. The disease was acquired, with onset at approximately thirty years of age, and partial, involving only the face and the upper limbs. The authors were able to observe the successive occurrence of the various symptoms: progressive lipoatrophy, hyperinsulinism, insulin-resistant diabetes, major lipid disturbances, and finally renal failure with a nephrotic syndrome and high blood pressure. Nosologic borders and physiopathology are discussed with a review of the literature.

摘要

报告了一例具有某些特殊特征的脂肪萎缩性糖尿病新病例。该疾病为后天获得性,发病年龄约为30岁,且为部分性,仅累及面部和上肢。作者能够观察到各种症状的相继出现:进行性脂肪萎缩、高胰岛素血症、胰岛素抵抗性糖尿病、严重脂质紊乱,最终发展为伴有肾病综合征和高血压的肾衰竭。结合文献综述对疾病分类边界和病理生理学进行了讨论。

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