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99m锝焦磷酸盐在神经肌肉疾病患者中的肌肉摄取。一项定量研究。

Muscle uptake of 99mtechnetium pyrophosphate in patients with neuromuscular disorder. A quantitative study.

作者信息

Messina C, Bonanno N, Baldari S, Vita G

出版信息

J Neurol Sci. 1982 Jan;53(1):1-7. doi: 10.1016/0022-510x(82)90075-2.

DOI:10.1016/0022-510x(82)90075-2
PMID:6276512
Abstract

99mTechnetium pyrophosphate (99mTc PYP) muscular scanning was carried out in 28 patients affected by neuromuscular diseases. To express the muscle tracer retention quantitatively, the soft tissue to bone uptake ratio was calculated in the thigh and in the lower leg. Significantly increased ratio values were found in all the patients with polymyositis and in most patients with different types of muscular dystrophy, while high values were seen in a few subjects with myasthenia gravis and with neurogenic disorders. These findings are compared with those of previous studies, and the factors playing a role in determining some discrepant observations are discussed. The use of 99mTc muscular scanning in the investigation of patients with suspected inflammatory myopathy is suggested.

摘要

对28例神经肌肉疾病患者进行了99m锝焦磷酸盐(99mTc PYP)肌肉扫描。为了定量表达肌肉示踪剂滞留情况,计算了大腿和小腿的软组织与骨骼摄取比值。在所有多发性肌炎患者以及大多数不同类型肌营养不良患者中均发现比值显著升高,而在少数重症肌无力和神经源性疾病患者中也出现了高值。将这些发现与先前研究的结果进行了比较,并讨论了导致一些差异观察结果的影响因素。建议将99mTc肌肉扫描用于疑似炎性肌病患者的检查。

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引用本文的文献

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Quantitative 3D scintigraphy shows increased muscular uptake of pyrophosphate in idiopathic inflammatory myopathy.定量三维闪烁扫描显示,在特发性炎性肌病中,肌肉对焦磷酸盐的摄取增加。
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