两例低肾素性高血压，推测是由于未知盐皮质激素分泌过多所致。

Two cases of low-renin hypertension thought to be due to excessive secretion of unknown mineralocorticoid.

作者信息

Haruyama K, Yamazaki M, Toki T, Fukuchi S

出版信息

Jpn Circ J. 1982 Feb;46(2):156-61. doi: 10.1253/jcj.46.156.

DOI:10.1253/jcj.46.156

Abstract

Two patients with low renin hypertension showing an increased urinary excretion with 17-KS, with normal level of plasma deoxycorticosterone and no signs of virilization were reported. Dexamethasone induced reduction in blood pressure and elevation of serum K, in spite of acceleration of the renin-angiotensin-aldosterone system. Thus, it has been inferred that the hypertension was not associated with adrenogenital syndrome but was due to excessive production of an unknown mineralocorticoid.

摘要

据报道，有两名低肾素性高血压患者，其17-酮类固醇尿排泄增加，血浆脱氧皮质酮水平正常且无男性化体征。尽管肾素-血管紧张素-醛固酮系统加速，但地塞米松仍使血压降低，血清钾升高。因此，据推测，该高血压与肾上腺性征异常综合征无关，而是由于一种未知盐皮质激素分泌过多所致。