Butkus D E, Jones F T
Biochim Biophys Acta. 1982 Feb 23;685(2):203-6. doi: 10.1016/0005-2736(82)90099-2.
Copper inhibits the hydro-osmotic response to vasopressin in the urinary bladder of Bufo marinus at a site proximal to cyclic AMP production. This effect is not reversed by washing in Cu2+ -free Ringer's solution but is overcome by serosal addition of reducing agents, suggesting that vasopressin responsiveness in this tissue is modulated by either the redox potential or the sulfhydryl content of the serosal membrane.
铜在环磷酸腺苷产生的近端位点抑制海蟾蜍膀胱对血管加压素的水渗透反应。在无铜离子的林格氏液中冲洗并不能逆转这种效应，但通过在浆膜侧添加还原剂可以克服这种效应，这表明该组织中血管加压素的反应性受浆膜的氧化还原电位或巯基含量的调节。
