高亲和力和低亲和力表皮生长因子受体的解离。低温、环己酰亚胺和佛波酯对高亲和力组分的抑制作用。 - Suppr

Suppr

超能文献

Resolution of high and low affinity epidermal growth factor receptors. Inhibition of high affinity component by low temperature, cycloheximide, and phorbol esters.

作者信息

King A C, Cuatrecasas P

出版信息

J Biol Chem. 1982 Mar 25;257(6):3053-60.

PMID:6277923

Abstract

摘要

相似文献

Resolution of high and low affinity epidermal growth factor receptors. Inhibition of high affinity component by low temperature, cycloheximide, and phorbol esters.高亲和力和低亲和力表皮生长因子受体的解离。低温、环己酰亚胺和佛波酯对高亲和力组分的抑制作用。

J Biol Chem. 1982 Mar 25;257(6):3053-60.

Inhibition of epidermal growth factor binding to mouse embryonal carcinoma cells by phorbol esters mediated by specific phorbol ester receptors.佛波酯通过特异性佛波酯受体介导对表皮生长因子与小鼠胚胎癌细胞结合的抑制作用。

J Biol Chem. 1981 Aug 10;256(15):7958-66.

Effect of retinoic acid and 12-O-tetradecanoyl phorbol-13-acetate on the binding of epidermal growth factor to its cellular receptors.维甲酸和十四酰佛波醇乙酯对表皮生长因子与其细胞受体结合的影响。

Biochim Biophys Acta. 1982 Aug 6;717(2):301-4. doi: 10.1016/0304-4165(82)90183-0.

Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells.表皮生长因子和强效佛波酯肿瘤启动子在人表皮样癌A431细胞中以相似但明显不同的方式诱导表皮生长因子受体磷酸化。

J Biol Chem. 1984 Feb 25;259(4):2559-67.

Inhibition of epidermal growth factor binding by phorbol esters, saccharin, and cyclamate and its implications in the mechanism of tumor promotion.

Carcinog Compr Surv. 1982;7:471-5.

Modulation of peptide binding to specific receptors on rat pituitary cells by tumor-promoting phorbol esters: decreased binding of thyrotropin-releasing hormone and somatostatin as well as epidermal growth factor.肿瘤促进剂佛波酯对大鼠垂体细胞上特定受体的肽结合的调节作用：促甲状腺激素释放激素、生长抑素以及表皮生长因子的结合减少。

Cancer Res. 1982 Nov;42(11):4375-81.

Epidermal growth factor and phorbol ester actions on human osteosarcoma cells. Characterization of response and nonresponsive cell lines.

J Biol Chem. 1982 Oct 25;257(20):12161-4.

Tumor-promoting phorbol diesters mediate phosphorylation of the epidermal growth factor receptor.促肿瘤佛波酯介导表皮生长因子受体的磷酸化。

J Biol Chem. 1984 Jul 10;259(13):8545-9.

Phorbol diester and epidermal growth factor receptors in 12-O-tetradecanoylphorbol-13-acetate-resistant and -sensitive mouse epidermal cells.12-O-十四酰佛波醇-13-乙酸酯抗性和敏感性小鼠表皮细胞中的佛波酯与表皮生长因子受体

Cancer Res. 1982 Aug;42(8):3093-7.

Epidermal growth factor regulates the expression of its own receptor.表皮生长因子调节其自身受体的表达。

Proc Natl Acad Sci U S A. 1985 Dec;82(24):8374-8. doi: 10.1073/pnas.82.24.8374.

引用本文的文献

Allosteric regulation of epidermal growth factor (EGF) receptor ligand binding by tyrosine kinase inhibitors.变构调节表皮生长因子（EGF）受体配体结合由酪氨酸激酶抑制剂。

J Biol Chem. 2018 Aug 31;293(35):13401-13414. doi: 10.1074/jbc.RA118.004139. Epub 2018 Jul 11.

A structural perspective on the regulation of the epidermal growth factor receptor.表皮生长因子受体调控的结构视角

Annu Rev Biochem. 2015;84:739-64. doi: 10.1146/annurev-biochem-060614-034402. Epub 2015 Jan 26.

Mechanisms of activation of receptor tyrosine kinases: monomers or dimers.受体酪氨酸激酶的激活机制：单体还是二聚体。

Cells. 2014 Apr 22;3(2):304-30. doi: 10.3390/cells3020304.

Kinetics of epidermal growth factor/receptor binding on cells measured by total internal reflection/fluorescence recovery after photobleaching.用全内反射/光漂白后荧光恢复测量细胞上表皮生长因子/受体结合的动力学。

J Fluoresc. 1991 Jun;1(2):113-28. doi: 10.1007/BF00865207.

Cetuximab and biomarkers in non-small-cell lung carcinoma.西妥昔单抗与非小细胞肺癌中的生物标志物

Biologics. 2012;6:221-31. doi: 10.2147/BTT.S24217. Epub 2012 Jul 13.

Negative co-operativity in the EGF receptor.EGF 受体的负协同性。

Biochem Soc Trans. 2012 Feb;40(1):15-9. doi: 10.1042/BST20110610.

The membrane-proximal intracellular domain of the epidermal growth factor receptor underlies negative cooperativity in ligand binding.表皮生长因子受体的膜近端胞内结构域在配体结合中具有负协同性。

J Biol Chem. 2011 Dec 30;286(52):45146-55. doi: 10.1074/jbc.M111.274175. Epub 2011 Nov 8.

The tethering arm of the EGF receptor is required for negative cooperativity and signal transduction.EGF 受体的连接臂对于负协同作用和信号转导是必需的。

J Biol Chem. 2011 Jan 14;286(2):1545-55. doi: 10.1074/jbc.M110.182899. Epub 2010 Nov 3.

The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding.表皮生长因子（EGF）受体的细胞内近膜结构域负责EGF结合的变构调节。

J Biol Chem. 2009 May 15;284(20):13570-13576. doi: 10.1074/jbc.M109.001487. Epub 2009 Mar 31.

Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system.表皮生长因子（EGF）结合亲和力的异质性源于聚集系统中的负协同效应。

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):112-7. doi: 10.1073/pnas.0707080105. Epub 2007 Dec 28.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验