Doutre L P, Perissat J, Dost C, Albalat F
J Chir (Paris). 1982 Feb;119(2):91-6.
Of 79 patients surviving after amputation of the rectum for cancer, local and regional recurrences occurred in 23 cases, in 3 out of 4 of these during the 2-year period following operation. Only 3 patients survived. This illustrates the frequency and serious nature of these recurrent lesions. Based on their experience, the authors consider the risk of recurrence to be doubled if one of the following factors is present : patient under 60 years of age, cancer located in the lower rectum, tumour over 4 cm in diameter, stages B or C according to Dukes' classification, an anaplastic or colloid structure. Enzyme assay and computed tomography are unfortunately not determining factors for early diagnosis and effective therapy of pelvic-peritoneal recurrences. the authors suggest, therefore, though it was never employed in their own series, that pre-operative irradiation could be of value, in those patients that have a high risk of developing local or regional recurrences. The general use of this technique is not suggested because its known inconveniences.
在79例因癌症行直肠切除术后存活的患者中，有23例发生了局部和区域复发，其中4例中有3例是在术后2年内复发的。只有3例患者存活。这说明了这些复发病变的频率和严重性。根据他们的经验，作者认为如果存在以下因素之一，复发风险会加倍：60岁以下的患者、癌位于直肠下段、肿瘤直径超过4厘米、根据杜克分类法为B期或C期、具有间变或胶样结构。遗憾的是，酶测定和计算机断层扫描并非盆腔腹膜复发早期诊断和有效治疗的决定性因素。因此，作者建议，尽管他们自己的系列研究中从未采用过，但术前放疗可能对那些有发生局部或区域复发高风险的患者有价值。不建议普遍使用这项技术，因为其存在已知的不便之处。
