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[肝阿米巴病:近期研究进展。161例病例报告(作者译)]

[Hepatic amebiasis: recent aspects. One hundred and sixty one case reports (author's transl)].

作者信息

Condat J M, Lecesne J L, Ticolat R, Niamkey E, Soubeyrand J, Merrien Y, Charmot G

出版信息

Sem Hop. 1982 Mar 11;58(10):579-89.

PMID:6278599
Abstract

The authors describe their experience of 16l patients (151 adults and 10 children) with hepatic amebiasis. Diagnosis and treatment were carried out at the Treichville Hospital University Center in Abidjan over a three-year period, from September 1976 to November 1979. Diagnosis was established without question in all cases. The indirect immunofluorescence reaction was particularly helpful. All patients were treated by metronidazole or it's derivatives. Semiology, course and therapy are described in detail. A comparison is made with cases published in the literature during the last 15 years. Most of the classical pictures were encountered in this study. The clinical picture may be misleading, for instance when it is suggestive of cancer or when jaundice is present. Immunology is particularly interesting in atypical forms. The authors insist on the unvarying and high morbidity due to this disease which accounts for 2% of all hospitalizations. Prognosis has improved, the mortality rate among adults was 4.5%. A fall in the number of surgical procedures was recorded. Only 10% of the patients underwent surgery. The therapeutic principles advocated by the authors are described. They can be used even when echotomography is not available, as is usually the case in regions where the disease is endemic.

摘要

作者描述了161例肝阿米巴病患者(151例成人和10例儿童)的治疗经验。1976年9月至1979年11月的三年间,在阿比让的特雷奇维尔医院大学中心进行了诊断和治疗。所有病例的诊断均明确无误。间接免疫荧光反应特别有用。所有患者均接受甲硝唑或其衍生物治疗。详细描述了症状学、病程和治疗方法。与过去15年文献中报道的病例进行了比较。本研究中遇到了大多数典型病例。临床表现可能会产生误导,例如当提示癌症或出现黄疸时。免疫学在非典型病例中特别有意义。作者强调该病发病率持续居高不下,占所有住院病例的2%。预后有所改善,成人死亡率为4.5%。手术例数有所下降。仅10%的患者接受了手术。描述了作者倡导的治疗原则。即使在没有超声断层扫描的情况下(在该病流行地区通常如此),这些原则也可应用。

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