[人工矿物纤维对蛋白质的吸附：体外实验]

[Adsorption of proteins by artificial mineral fibers: in vitro experiments].

作者信息

Valentino M, Governa M, Curatola G, Fiorini R M, Lo Martire N

出版信息

Boll Soc Ital Biol Sper. 1982 Jan;58(1-2):80-6.

Abstract

Since previous studies reported that in vitro some proteins and phospholipids were absorbed by asbestos fibres, namely chrysotile, in this study, man made filamentous glass fibers are been tested in vitro at the presence of proteins. The objective was to obtain evidence to evaluate whether continuous glass fibers have a behaviour similar to asbestos fibres. A sample of chrysotile fibres was used as control. Uptake of bovine serum albumin and horse spleen ferritin on these continuous glass fibres has been observed. However on glass fibres adsorbed less proteins per weight unit (22 mg/g and 12 mg/g respectively for albumin and ferritin) than asbestos chrysotile fibres (42 mg/g and 49 mg/g respectively for albumin and ferritin).

摘要

由于先前的研究报道，在体外一些蛋白质和磷脂会被石棉纤维（即温石棉）吸附，因此在本研究中，人造丝状玻璃纤维在有蛋白质存在的情况下进行了体外测试。目的是获取证据以评估连续玻璃纤维是否具有与石棉纤维相似的行为。使用温石棉纤维样品作为对照。已观察到牛血清白蛋白和马脾铁蛋白在这些连续玻璃纤维上的摄取情况。然而，玻璃纤维每重量单位吸附的蛋白质（白蛋白和铁蛋白分别为22毫克/克和12毫克/克）比温石棉纤维（白蛋白和铁蛋白分别为42毫克/克和49毫克/克）少。