Sanchez N P, Mihm M C
J Am Acad Dermatol. 1982 Mar;6(3):378-88. doi: 10.1016/s0190-9622(82)70033-7.
The clinical classification of the vulvar dystrophies has traditionally been difficult because most of these lesions present as a white hyperkeratotic patch. An international committee for the study of the vulva designed a histologic classification that consists of: I, hyperplastic type, with or without atypia; II, lichen sclerosus; and, III, mixed dystrophy, with or without atypia. A new classification and a fourth type are proposed by us to sort out a group of strictly benign dermatoses with distinctive histopathologic features which can present clinically as a white patch in the vulva; these are best designated as benign dermatoses. In addition to these, squamous cell carcinoma in situ and Paget's disease may also be manifested as a white patch. Hence, a classification of vulvar diseases with new nomenclature is presented from the dermatopathologist's perspective, based on histologic and clinical features.
传统上，外阴营养不良的临床分类一直很困难，因为这些病变大多表现为白色角化过度斑块。一个国际外阴研究委员会设计了一种组织学分类方法，包括：I型，增生型，有或无异型性；II型，硬化性苔藓；III型，混合性营养不良，有或无异型性。我们提出了一种新的分类方法和第四种类型，以梳理出一组具有独特组织病理学特征的严格良性皮肤病，这些皮肤病在临床上可表现为外阴白色斑块；最好将其称为良性皮肤病。除此之外，原位鳞状细胞癌和佩吉特病也可能表现为白色斑块。因此，从皮肤病理学家的角度出发，基于组织学和临床特征，提出了一种具有新命名法的外阴疾病分类。
