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愈合早期心肌梗死患者在自行车测力计测试期间的[99mTc-焦磷酸盐闪烁扫描指数]

[99mTc-pyrophosphate scintigraphic indices during the bicycle ergometry test in myocardial infarct in the early phase of healing].

作者信息

Vinogradov A V, Sycheva I M, Demidov A S, Rylova A K, Gel'fand I N

出版信息

Kardiologiia. 1982 Feb;22(2):93-7.

PMID:6279955
Abstract

Scintigraphy with 99mTc-pyrophosphate during bicycle ergometry has been undertaken in 32 patients with myocardial infarction in the early phase of its healing. There were 3 scintigraphic investigations: one during bicycle ergometry and two control ones - before and the day after the test. The determination of changes in the degree of 99mTc-pyrophosphate accumulation under the influence of the exercise in patients with myocardial infarction in the early phase of its healing permitted the authors to detect several variants in the time course of scintigraphic values. Drop or rise of concentration of the labelled pyrophosphate at the height of the bicycle ergometry test compared to the data obtained prior to it are apparently due to changed bloodflow in the focus of lesion during exercise. Changes in the character and intensity of accumulation of the radiodrug after bicycle ergometry can be explained in the majority of cases by increase of metabolic disorders in the myocardium, supervening during the exercise, and in some patients, possibly, to sustained decrease of bloodflow in the affected area of the cardiac muscle.

摘要

对32例处于愈合早期的心肌梗死患者在踏车运动试验期间进行了99m锝焦磷酸盐闪烁扫描检查。共进行了3次闪烁扫描检查:1次在踏车运动试验期间,另外2次为对照检查——分别在试验前和试验后一天。对处于愈合早期的心肌梗死患者在运动影响下99m锝焦磷酸盐蓄积程度变化的测定,使作者能够检测到闪烁扫描值随时间变化的几种情况。与试验前获得的数据相比,在踏车运动试验高峰时标记焦磷酸盐浓度下降或升高,显然是由于运动期间病变部位血流变化所致。在大多数情况下,踏车运动试验后放射性药物蓄积特征和强度的变化可解释为运动期间心肌代谢紊乱加剧,而在一些患者中,可能是由于心肌受累区域血流持续减少。

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