Tonak J, Beck H
Langenbecks Arch Chir. 1981;355:157-63. doi: 10.1007/BF01286832.
Hyperthermic perfusion was used in 15 adult patients with soft tissue sarcoma of the limbs. Only patients were selected with prognostically unfavorable or recurrent tumors, which were excised with a limited safety margin. Three patients died from pulmonary metastases 16, 24 and 34 months after perfusion. In 2 patients a local recurrence developed. Ten patients are alive and free of recurrence. The follow-up period ranges from 7 - 47 months with a median of 30 months. These results encourage the further use of hyperthermic perfusion.
对15例成年肢体软组织肉瘤患者采用了热灌注治疗。仅选择预后不良或复发的肿瘤患者,手术切除时安全切缘有限。3例患者在灌注后16、24和34个月死于肺转移。2例患者出现局部复发。10例患者存活且无复发。随访时间为7至47个月,中位时间为30个月。这些结果鼓励进一步应用热灌注治疗。