Helsley G C, Strupczewski J, Woodward D L
J Med Chem. 1978 Mar;21(3):309-12. doi: 10.1021/jm00201a018.
A series of 3-[2-(phenoxypiperidyl)-ethyl]indoles was synthesized and evaluated for hypotensive activity in the spontaneous hypertensive rat. Maximum hypotensive activity appeared when the phenoxy substituent was para substituted and occupied the 4 position of the piperidine ring.
