Paillas J E, Grisoli F, Hassoun J, Torres-Garcia T, De Laforte C
Sem Hop. 1982 Apr 8;58(14):851-6.
The authors report their experience of 84 patients with oligodendroglioma seen over a 34 year period. The low incidence of these brain tumors is underlined. Oligodendroglioma is the most epileptogenic of brain tumors. The clinical picture may resemble "essential" epilepsy. Normal EEG should be considered suspect in confirmed epileptic children and adolescents since oligodendroglioma is the most common of all tumors which induce long-standing epilepsy. Emphasis is put on the importance of computerized tomography and radionuclide scanning for early detection of these tumors. Both procedures are very helpful for deciding on the best operative approach and for determining whether the lesion is malignant or not. The authors advise tumorectomy, which should be as complete as possible, followed by systematic radiotherapy, even if histopathological criteria indicate a benign tumor. With this therapeutic regimen mean survival rates are significantly higher than those published previously.
作者报告了他们在34年期间对84例少突胶质细胞瘤患者的治疗经验。强调了这些脑肿瘤的低发病率。少突胶质细胞瘤是最易引发癫痫的脑肿瘤。其临床表现可能类似“原发性”癫痫。对于确诊为癫痫的儿童和青少年，正常脑电图应被视为可疑，因为少突胶质细胞瘤是所有引发长期癫痫的肿瘤中最常见的。重点强调了计算机断层扫描和放射性核素扫描对于早期发现这些肿瘤的重要性。这两种检查方法对于确定最佳手术方式以及判断病变是否为恶性都非常有帮助。作者建议进行尽可能彻底的肿瘤切除术，随后进行系统放疗，即使组织病理学标准显示为良性肿瘤。采用这种治疗方案，平均生存率显著高于先前公布的水平。
