摄入氟化物后的腺苷酸环化酶活性。

Adenyl cyclase activity following fluoride ingestion.

作者信息

Susheela A K, Singh M

出版信息

Toxicol Lett. 1982 Feb;10(2-3):209-12. doi: 10.1016/0378-4274(82)90076-5.

PMID:6281946

Abstract

Adenyl cyclase activity and fluoride content were investigated in various tissues of adult rabbits given NaF (10 mg/kg body wt./day) orally for 6 months. The activity of adenyl cyclase increased significantly in bone, liver, and kidney, whereas it was unchanged in skeletal muscle following fluoride ingestion. The levels of fluoride were elevated in serum and all the tissues investigated following fluoride ingestion; bone revealed the highest percentage increase and skeletal muscle the lowest.

摘要

对成年兔口服氟化钠（10毫克/千克体重/天）6个月后，对其各种组织中的腺苷酸环化酶活性和氟含量进行了研究。摄入氟后，骨、肝和肾中的腺苷酸环化酶活性显著增加，而骨骼肌中的活性未发生变化。摄入氟后，血清和所有研究组织中的氟含量均升高；骨中氟含量增加的百分比最高，骨骼肌中最低。