Hirsch V M, Farrow C S
Can Vet J. 1981 Sep;22(9):271-6.
The clinical, laboratory, radiographic and pathological findings of two dogs with similar neoplasms are described. Both dogs were mature males of a large breed and had pleural and abdominal effusions containing neoplastic cells. Diffuse scirrhous thickening of the pleura and serosal surfaces was a prominent feature. A fibrous layer containing nests of neoplastic, epithelial-like cells was present on serosal surfaces. The morphological appearance of the cells was suggestive of either an atypical sclerosing mesothelioma or a scirrhous carcinoma. On the basis of ultrastructural and differential staining characteristics, a diagnosis of a scirrhous carcinoma of undetermined primary origin was made in one case and of prostatic urethral origin in the other case.
描述了两只患有相似肿瘤的犬的临床、实验室、影像学和病理学检查结果。两只犬均为大型犬种的成年雄性，胸腔和腹腔积液中含有肿瘤细胞。胸膜和浆膜表面弥漫性硬癌性增厚是一个突出特征。浆膜表面存在含有肿瘤性上皮样细胞巢的纤维层。细胞的形态学表现提示非典型硬化性间皮瘤或硬癌。根据超微结构和鉴别染色特征，一例诊断为原发灶不明的硬癌，另一例诊断为前列腺尿道起源的硬癌。
