Pichler E, Jürgenssen O A, Reinartz G, Kärcher K H, Helmer F, Esch W, Krepler R, Urban C, Kurz R, Sauer H, Hubmer G, Hackl A, Kahr E, Kaulfersch W, Haas H, Menardi G, Hüttenberger J, Krepler P, Flamm C, Wurnig P, Rosenkranz A, Busch U, Messner H, Brandesky G, Mutz I, Tulzer W, Hartl H, Howanietz L, Rücker J
Dtsch Med Wochenschr. 1981 Sep 25;106(39):1248-53. doi: 10.1055/s-2008-1070491.
Uniform treatment based on the therapeutic approach of the 1st and 2nd US National Wilms' Tumor Study was decided on in March 1976 by paediatricians, surgeons, urologists and radiotherapists in Austria. Wilms' tumour was diagnosed in 34 children between 1 january 1976 an 29 february 1980 (stage I: n = 11, stage II: n = 8, stage III: n = 8, stage IV: n = 7). Parents of two children refused treatments; both children have since died of metastases. Of the remaining 32 children 29 (90.6%) are alive, 10 for more than 4, 15 for more than 3 and 19 for more than 2 years after diagnosis. 21 children are without need of treatment. Three children have died, one due to postoperative complications, one due to haemorrhagic chickenpox, but free of tumour, and one after insufficient treatment. Two of the five children with a recurrence between 2 1/4 to 15 months after diagnosis had been treated inadequately in the initial phase. The tumour free survival rate in 74.2%. Two children with early occurring or recurrent lung metastases have survived for 53 1/2 and 54 months up to now.
1976年3月，奥地利的儿科医生、外科医生、泌尿科医生和放射治疗师决定采用美国第一次和第二次国家肾母细胞瘤研究的治疗方法进行统一治疗。1976年1月1日至1980年2月29日期间，34名儿童被诊断出患有肾母细胞瘤（I期：n = 11，II期：n = 8，III期：n = 8，IV期：n = 7）。两名儿童的父母拒绝治疗；这两名儿童均因转移而死亡。其余32名儿童中，29名（90.6%）存活，其中10名在诊断后存活超过4年，15名超过3年，19名超过2年。21名儿童无需治疗。3名儿童死亡，1名死于术后并发症，1名死于出血性水痘但无肿瘤，1名死于治疗不足。5名在诊断后2.25至15个月复发的儿童中有2名在初始阶段治疗不当。无瘤生存率为74.2%。两名早期出现或复发肺转移的儿童至今已存活53.5个月和54个月。
