人肺肿瘤细胞中的生物胺代谢产物：组织化学和质谱法证明
Biogenic amine metabolites in human lung tumor cells: histochemical and mass-spectrographic demonstration.
作者信息
Pettengill O S, Bacopoulos N G, Sorenson G D
出版信息
Life Sci. 1982 Apr 19;30(16):1355-60. doi: 10.1016/0024-3205(82)90020-0.
PMID:6283290
Abstract
Three continuous cell lines isolated from small cell carcinoma of the lung (SCCL) have been examined for their ability to take up and metabolize the biogenic amine precursors, L-DOPA and 5-hydroxytryptophane (5-HTP). In two of the three lines formaldehyde-induced fluorescence (FIF) and mass-spectrographic analysis indicated specific uptake and metabolism of L-DOPA and 5-HTP.
摘要
已对从肺小细胞癌（SCCL）分离出的三种连续细胞系摄取和代谢生物胺前体L-多巴和5-羟色氨酸（5-HTP）的能力进行了检测。在这三种细胞系中的两种中，甲醛诱导荧光（FIF）和质谱分析表明存在L-多巴和5-HTP的特异性摄取和代谢。
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