Lewis R A, Sumner A J
Neurology. 1982 Jun;32(6):592-6. doi: 10.1212/wnl.32.6.592.
We compared the electrodiagnostic studies of 40 patients with chronic acquired demyelinative neuropathy and 18 patients with familial demyelinative neuropathy. Patients with acquired neuropathy had differential slowing of conduction velocity when distal latencies were compared with more proximal conduction velocities in the same nerve, when equivalent segments of different nerves were compared, and when dispersion of compound motor action potentials was examined. Conduction block was noted in some patients. Patients with familial disease had uniform conduction slowly of all nerve segments, and conduction block was not seen. Chronic acquired demyelinative neuropathy is characterized by multifocal slowing of nerve conduction, whereas familial demyelinative neuropathy is characterized by uniform conduction slowing.
我们比较了40例慢性获得性脱髓鞘性神经病患者和18例家族性脱髓鞘性神经病患者的电诊断研究结果。获得性神经病患者在将同一神经的远端潜伏期与更近端的传导速度进行比较时、在比较不同神经的等效节段时以及在检查复合运动动作电位的离散度时，均存在传导速度的差异减慢。部分患者存在传导阻滞。家族性疾病患者所有神经节段的传导均均匀减慢，未见传导阻滞。慢性获得性脱髓鞘性神经病的特征是神经传导多灶性减慢，而家族性脱髓鞘性神经病的特征是传导均匀减慢。
