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[垂体腺瘤与致甲状腺性甲状腺功能亢进症同时发生]

[Simultaneous occurrence of pituitary adenoma and thyrogenic hyperthyroidism].

作者信息

Góth M, Szabolcs I, Irsy G, Szilágyi G, Afra D, Pásztor E

出版信息

Z Gesamte Inn Med. 1982 Mar 15;37(6):183-6.

PMID:6283751
Abstract

Subtotal tumour removal had been performed in a 34-year-old female patient for an extensive intra- and suprasellar expansive process. The considerably increased prolactin level did not decrease postoperatively, but normalised only after a three months bromocriptine treatment. The primary hyperthyroidism has been recovering after administering methimazolum. In a second case was reported on a 65-year-old female patient, suffering from rachitic dwarfism, stenosis of the aortic valve and tumour of the hypophysis, causing acromegaly, whose diabetes mellitus of contrainsular type could have been hardly balanced with insulin of a 128-unit-dose daily, and whose hyperthyroidism was due to an autonomous adenoma of the thyroid gland, first I-131 treatment was administered and she got into an euthyroid state. Six weeks following the removal of the acidophilic adenoma of the hypophysis administration of insulin could have been ceased, and the results of her growth hormone became normal. The clinical picture partly corresponds with Troell-Junet's syndrome.

摘要

对一名34岁女性患者进行了肿瘤次全切除,该患者存在广泛的鞍内和鞍上扩张性病变。术后催乳素水平显著升高并未下降,仅在接受三个月溴隐亭治疗后恢复正常。服用甲巯咪唑后原发性甲状腺功能亢进症已恢复。报道的第二例是一名65岁女性患者,患有佝偻病性侏儒症、主动脉瓣狭窄和垂体瘤,导致肢端肥大症,其胰岛细胞型糖尿病每日128单位剂量的胰岛素几乎难以控制,其甲状腺功能亢进症是由甲状腺自主腺瘤引起的,首先进行了I-131治疗,她进入了甲状腺功能正常状态。垂体嗜酸性腺瘤切除六周后可以停止使用胰岛素,其生长激素结果恢复正常。临床表现部分符合特罗尔-朱内综合征。

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1
[Simultaneous occurrence of pituitary adenoma and thyrogenic hyperthyroidism].[垂体腺瘤与致甲状腺性甲状腺功能亢进症同时发生]
Z Gesamte Inn Med. 1982 Mar 15;37(6):183-6.
2
[Coincidence of hypophyseal adenoma and thyrogenic hyperthyroidism].[垂体腺瘤与致甲状腺性甲状腺功能亢进症的巧合]
Z Gesamte Inn Med. 1985 Oct 15;40(20):606-8.
3
[Pituitary adenoma in acromegaly-gigantism. Macroscopic, histological and ultrastructural study].[肢端肥大症-巨人症中的垂体腺瘤。宏观、组织学及超微结构研究]
Neurochirurgie. 1973 May;19(2):Suppl 2:117-62.
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[Endocrine disorders in pituitary tumors].[垂体瘤中的内分泌紊乱]
Helv Med Acta. 1963 Nov;30(4):487-94.
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[Stereotaxic cryodestruction of hypophyseal tumors].[垂体肿瘤的立体定向冷冻毁损术]
Vopr Neirokhir. 1973 Sep-Oct;37(5):8-14.
6
Hyperthyroidism due to thyrotropin-producing pituitary chromophobe adenoma.促甲状腺素分泌型垂体嗜色细胞瘤所致甲状腺功能亢进症。
N Engl J Med. 1970 Nov 12;283(20):1077-80. doi: 10.1056/NEJM197011122832003.
7
Acromegaly and thyrotoxicosis induced by a GH- and TSH-producing pituitary tumour which also contained prolactin.由同时分泌生长激素、促甲状腺激素且含有催乳素的垂体肿瘤引起的肢端肥大症和甲状腺毒症。
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8
Acromegaly and diabetes mellitus associated with hyperthyroidism.肢端肥大症与甲状腺功能亢进症相关的糖尿病。
Neuro Endocrinol Lett. 2014;35(3):171-4.
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Chromophobe pituitary adenoma with acromegaly and TSH-induced hyperthyroidism associated with parathyroid adenoma. Acromegaly and parathyroid adenoma.伴有肢端肥大症和促甲状腺激素诱导的甲状腺功能亢进及甲状旁腺腺瘤的嫌色细胞垂体腺瘤。肢端肥大症和甲状旁腺腺瘤。
Acta Endocrinol (Copenh). 1969 Jan;60(1):157-72. doi: 10.1530/acta.0.0600157.
10
[Hypophyseal intratumoral apoplexy. Apropos of 5 cases].[垂体瘤内卒中。附5例报告]
Rev Clin Esp. 1982 Mar 31;164(6):359-62.