Kriek N P, Sly M R, du Bruyn D B, de Klerk W A, Renan M J, Van Schalkwyk D J, Van Rensburg S J
Br J Exp Pathol. 1982 Jun;63(3):254-68.
Two groups of 13 young baboons, each consisting of 8 males and 8 females, were fed on either high- or low-bran diets (based on wheat of either high or low extraction rate) for a period of 26 months. All animals grew well and remained in good condition throughout. Male (but not female) baboons on the high-bran diet had lower (p less than 0.05) concentrations of zinc in serum and bone, despite a low phytate: zinc molar ratio and a high intake of zinc. Particle-induced X-ray emission analysis showed there to be lower concentrations of calcium, copper, zinc, sulphur, potassium and nickel in the livers of baboons on the high-bran diet (P less than 0.005). Baboons on the low-bran diet passed smaller quantities of softer faeces, they had fewer nodules of lymphoid tissue in the distal portion of the colon (P less than 0.05), and within mucosal microherniations of their ileo-caecal valves the epithelial cells showed a greater tendency to squamous transformation (P less than 0.05). Mucosal microherniations of the ileo-caecal valves tended to be more frequent and larger in size (P less than 0.05) in animals of the low-bran group. Morphometrical studies did not reveal any differences in the general structural development of the digestive tract. The high-bran diet had no effect on serum cholesterol concentrations, nor on the incidence or severity of atherosclerotic lesions of the aorta.
两组各有13只幼年狒狒，每组包括8只雄性和8只雌性，分别用高麸或低麸饮食（基于高或低出粉率的小麦）喂养26个月。所有动物生长良好，始终状况良好。食用高麸饮食的雄性（而非雌性）狒狒血清和骨骼中的锌浓度较低（p<0.05），尽管植酸盐：锌的摩尔比低且锌摄入量高。粒子诱导X射线发射分析显示，食用高麸饮食的狒狒肝脏中钙、铜、锌、硫、钾和镍的浓度较低（P<0.005）。食用低麸饮食的狒狒排出的软粪便量较少，结肠远端的淋巴组织结节较少（P<0.05），在其回盲瓣的黏膜微疝内，上皮细胞显示出更大的鳞状化生倾向（P<0.05）。低麸组动物回盲瓣的黏膜微疝往往更频繁且尺寸更大（P<0.05）。形态计量学研究未发现消化道总体结构发育有任何差异。高麸饮食对血清胆固醇浓度以及主动脉粥样硬化病变的发生率或严重程度均无影响。
