Civantos F, Penneys N S, Haines H
J Invest Dermatol. 1982 Aug;79(2):79-80. doi: 10.1111/1523-1747.ep12500029.
Using an immunohistochemical method, we could not detect cytomegalovirus antigens in the tissue of Kaposi's sarcoma but could in the cells of control sections from tissues known to be infected by that virus. Our results are consistent with the hypothesis that high antibody titers to cytomegalovirus found in patients with Kaposi's sarcoma are not due to infection of neoplastic cells by the virus, as a secondary event; our data supports the conclusions of others that exposure to cytomegalovirus may be a primary event in the pathogenesis of Kaposi's sarcoma.
通过免疫组织化学方法，我们在卡波西肉瘤组织中未检测到巨细胞病毒抗原，但在已知感染该病毒的组织对照切片细胞中检测到了。我们的结果与以下假设一致：在卡波西肉瘤患者中发现的针对巨细胞病毒的高抗体滴度并非由于病毒作为继发事件感染肿瘤细胞所致；我们的数据支持其他人的结论，即接触巨细胞病毒可能是卡波西肉瘤发病机制中的一个原发事件。
