Twomey P, Montgomery C, Clark O
JAMA. 1982 Aug 6;248(5):581-3.
Although on a weight basis the adrenal gland is the most common site of extranodal spread from lung cancer, antemortem diagnosis and successful therapy of adrenal metastasis are rare. We have treated two patients with apparently solitary metastases in the adrenal gland from large-cell carcinomas of the lung using a combination of adrenalectomy and vigorous therapy to the primary site. Both patients experienced symptomatic relief, and, in contrast to the expected short survival in lung cancer with distant metastasis, they remain well six years and 14 years after treatment.
尽管从重量比例来看，肾上腺是肺癌最常见的结外转移部位，但肾上腺转移瘤的生前诊断和成功治疗却很罕见。我们采用肾上腺切除术并对原发部位进行积极治疗，治疗了两名患有明显孤立性肾上腺转移瘤的大细胞肺癌患者。两名患者均症状缓解，而且与预期的伴有远处转移的肺癌患者短期生存情况不同，他们在治疗后分别存活了6年和14年，目前状况良好。
