David B, Reiffers J, Broustet A
Sem Hop. 1982 May 13;58(19):1157-60.
In adults, acute lymphoblastic leukemia (ALL) is less frequent and less clearly defined than in children. A retrospective study of fifty adult patients with ALL was carried out. Findings were similar to those reported in previous studies. Complete remission was achieved in 86% of patients. This rate is similar to that recorded in children with ALL. Median survival (twenty months) was shorter than in childhood because of frequent relapses. Various factors of prognostic value are discussed. Problems encountered in attempting immunological classification are studied. Prognosis seems to be related to the intensiveness of induction therapy and the choice of maintenance therapy regimen.
在成人中，急性淋巴细胞白血病（ALL）的发病率低于儿童，且定义不如儿童明确。对50例成年ALL患者进行了一项回顾性研究。研究结果与先前研究报告的结果相似。86%的患者实现了完全缓解。这一比率与儿童ALL患者的记录相似。由于频繁复发，成年患者的中位生存期（20个月）短于儿童。文中讨论了各种具有预后价值的因素。研究了在尝试进行免疫分类时遇到的问题。预后似乎与诱导治疗的强度和维持治疗方案的选择有关。
