Verma K, Bhargava D K
Acta Cytol. 1982 May-Jun;26(3):311-6.
Laparoscopic examination guided biopsy and cytologic examination of samples obtained by aspiration, brush or scrape from the liver or gallbladder were performed on 26 patients suspected of having hepatic or gallbladder neoplasia. Laparoscopic findings were diagnostic of hepatic neoplasia (primary or secondary) in 13 cases and gallbladder carcinoma in 9 cases. The yields of positive diagnoses on biopsy alone, cytology alone and combined biopsy and cytology were 11 (84.6%), 11 (84.6%) and 12 (92.3%), respectively, in cases of hepatic neoplasia and 4 (44.4%), 5 (55.5%) and 5 (55.5%), respectively, in cases of gallbladder carcinoma. The cytologic typing concurred with the histologic typing in six of ten cases (60%) of hepatic neoplasia and all four cases (100%) of gallbladder carcinoma. It is suggested that cytologic examination be used as an adjunct to histologic examination of guided biopsies in the diagnosis of hepatic neoplasia. It is also concluded that it is possible to make a tissue diagnosis in patients with gallbladder carcinoma by obtaining material for cytology and biopsy through laparoscopy.
对26例疑似肝或胆囊肿瘤的患者进行了腹腔镜检查引导下的活检，并对通过抽吸、刷检或刮擦从肝脏或胆囊获取的样本进行了细胞学检查。腹腔镜检查结果显示，13例诊断为肝肿瘤（原发性或继发性），9例诊断为胆囊癌。在肝肿瘤病例中，单纯活检、单纯细胞学检查以及活检与细胞学联合检查的阳性诊断率分别为11例（84.6%）、11例（84.6%）和12例（92.3%）；在胆囊癌病例中，上述三项检查的阳性诊断率分别为4例（44.4%）、5例（55.5%）和5例（55.5%）。在10例肝肿瘤病例中的6例（60%）以及4例胆囊癌病例中的所有4例（100%），细胞学分型与组织学分型一致。建议在肝肿瘤诊断中，将细胞学检查作为引导活检组织学检查的辅助手段。还得出结论，通过腹腔镜获取细胞学和活检材料，对胆囊癌患者进行组织学诊断是可行的。
