Gorman A L, Woolum J C, Cornwall M C
Biophys J. 1982 Jun;38(3):319-22. doi: 10.1016/S0006-3495(82)84565-7.
The ionic selectivity of the Ca(2+)-activated K(+) channel of Aplysia neurons and of the light-dependent K(+) channel of Pecten photoreceptors to metal and organic cations was studied. The selectivity sequence determined from reversal potential measurements is T1(+) K(+) > Rb(+) > NH(+) (4) > Cs(+) > Na(+), Li(+) and is identical to the sequence determined previously for voltage-dependent K(+) channels in a variety of tissues. Our results suggest that some physical aspect of the K(+) channel is conserved in phyllogenetically different tissues and cells.
对海兔神经元的钙激活钾通道以及扇贝光感受器的光依赖性钾通道对金属阳离子和有机阳离子的离子选择性进行了研究。通过反转电位测量确定的选择性顺序为:Tl⁺>K⁺>Rb⁺>NH₄⁺>Cs⁺>Na⁺、Li⁺,这与先前在多种组织中针对电压依赖性钾通道所确定的顺序相同。我们的结果表明,钾通道的某些物理特性在系统发育上不同的组织和细胞中是保守的。