钙离子激活的和光依赖性钾通道对单价阳离子的选择性。
Selectivity of the Ca2+-activated and light-dependent K+ channels for monovalent cations.
作者信息
Gorman A L, Woolum J C, Cornwall M C
出版信息
Biophys J. 1982 Jun;38(3):319-22. doi: 10.1016/S0006-3495(82)84565-7.
Abstract
The ionic selectivity of the Ca(2+)-activated K(+) channel of Aplysia neurons and of the light-dependent K(+) channel of Pecten photoreceptors to metal and organic cations was studied. The selectivity sequence determined from reversal potential measurements is T1(+) K(+) > Rb(+) > NH(+) (4) > Cs(+) > Na(+), Li(+) and is identical to the sequence determined previously for voltage-dependent K(+) channels in a variety of tissues. Our results suggest that some physical aspect of the K(+) channel is conserved in phyllogenetically different tissues and cells.
摘要
对海兔神经元的钙激活钾通道以及扇贝光感受器的光依赖性钾通道对金属阳离子和有机阳离子的离子选择性进行了研究。通过反转电位测量确定的选择性顺序为：Tl⁺＞K⁺＞Rb⁺＞NH₄⁺＞Cs⁺＞Na⁺、Li⁺，这与先前在多种组织中针对电压依赖性钾通道所确定的顺序相同。我们的结果表明，钾通道的某些物理特性在系统发育上不同的组织和细胞中是保守的。
相似文献
1
Selectivity of the Ca2+-activated and light-dependent K+ channels for monovalent cations.钙离子激活的和光依赖性钾通道对单价阳离子的选择性。
Biophys J. 1982 Jun;38(3):319-22. doi: 10.1016/S0006-3495(82)84565-7.
2
The cation selectivity and voltage dependence of the light-activated potassium conductance in scallop distal photoreceptor.扇贝远端光感受器中光激活钾电导的阳离子选择性和电压依赖性。
J Physiol. 1983 Jul;340:287-305. doi: 10.1113/jphysiol.1983.sp014763.
3
External monovalent cations that impede the closing of K channels.阻碍钾通道关闭的细胞外单价阳离子。
J Gen Physiol. 1986 May;87(5):795-816. doi: 10.1085/jgp.87.5.795.
4
Effects of permeant monovalent cations on end-plate channels.可渗透单价阳离子对终板通道的影响。
J Physiol. 1979 Mar;288:509-28.
5
The potential-dependent K+ channel in molluscan neurones is organized in a cluster of elementary channels.软体动物神经元中电位依赖性钾通道由一组基本通道组成。
Biochim Biophys Acta. 1984 Jun 13;773(1):132-42. doi: 10.1016/0005-2736(84)90558-3.
6
Multi-ion conduction and selectivity in the high-conductance Ca++-activated K+ channel from skeletal muscle.骨骼肌高电导钙激活钾通道中的多离子传导与选择性
Biophys J. 1986 Dec;50(6):1025-34. doi: 10.1016/S0006-3495(86)83546-9.
7
Sodium permeability of a cloned small-conductance calcium-activated potassium channel.一种克隆的小电导钙激活钾通道的钠通透性
Biophys J. 2005 Nov;89(5):3111-9. doi: 10.1529/biophysj.105.069542. Epub 2005 Sep 2.
8
Ion conductance and ion selectivity of potassium channels in snail neurones.蜗牛神经元中钾通道的离子电导和离子选择性
J Membr Biol. 1980 Dec 15;57(2):103-18. doi: 10.1007/BF01868997.
9
Ca2+ activated K+ conductance in molluscan neurones.
Cell Calcium. 1983 Dec;4(5-6):387-405. doi: 10.1016/0143-4160(83)90016-7.
10
Regulation of connexin hemichannels by monovalent cations.单价阳离子对连接蛋白半通道的调节
J Gen Physiol. 2006 Jan;127(1):67-75. doi: 10.1085/jgp.200509397.
引用本文的文献
1
Calcium Enhances Thallium Uptake in Green Cabbage ( var. L.).钙增强甘蓝（var. L.）对铊的摄取。
Int J Environ Res Public Health. 2022 Dec 20;20(1):4. doi: 10.3390/ijerph20010004.
2
Phencyclidine (PCP), in Nanomolar Concentrations, Binds to Synaptosomes and Blocks Certain Potassium Channels: Covalent Labeling of K Channels with PCP.苯环己哌啶（PCP）在纳摩尔浓度下与突触体结合并阻断某些钾通道：PCP对钾通道的共价标记
Biophys J. 1984 Jan;45(1):119-21. doi: 10.1016/S0006-3495(84)84132-6.
3
Interaction of the Depolarization-Activated K Channel of Samanea saman with Inorganic Ions: A Patch-Clamp Study.萨曼莎相思树去极化激活钾通道与无机离子的相互作用：膜片钳研究。
Plant Physiol. 1990 Oct;94(2):424-31. doi: 10.1104/pp.94.2.424.
4
On the gating mechanisms of the light-dependent conductance in Pecten hyperpolarizing photoreceptors: does light remove inactivation in voltage-dependent K channels?关于扇贝超极化光感受器中光依赖性电导的门控机制：光是否消除了电压依赖性钾通道的失活？
J Gen Physiol. 2005 May;125(5):455-64. doi: 10.1085/jgp.200509269. Epub 2005 Apr 11.
5
Fast single-channel measurements resolve the blocking effect of Cs+ on the K+ channel.快速单通道测量解析了Cs+对K+通道的阻断作用。
Biophys J. 1994 Jul;67(1):120-9. doi: 10.1016/S0006-3495(94)80461-8.
6
FMRFamide and membrane stretch as activators of the Aplysia S-channel.FMRF酰胺和膜拉伸作为海兔S通道的激活剂。
Biophys J. 1994 Jan;66(1):46-58. doi: 10.1016/S0006-3495(94)80749-0.
7
The cation selectivity and voltage dependence of the light-activated potassium conductance in scallop distal photoreceptor.扇贝远端光感受器中光激活钾电导的阳离子选择性和电压依赖性。
J Physiol. 1983 Jul;340:287-305. doi: 10.1113/jphysiol.1983.sp014763.
8
Ionic currents in two strains of rat anterior pituitary tumor cells.两种大鼠垂体前叶肿瘤细胞系中的离子电流
J Gen Physiol. 1984 Mar;83(3):309-39. doi: 10.1085/jgp.83.3.309.
9
Phencyclidine in nanomolar concentrations binds to synaptosomes and blocks certain potassium channels.纳摩尔浓度的苯环利定与突触体结合并阻断某些钾通道。
Proc Natl Acad Sci U S A. 1983 Jun;80(12):3855-9. doi: 10.1073/pnas.80.12.3855.
10
Conduction and selectivity in potassium channels.钾通道中的传导与选择性
J Membr Biol. 1983;71(1-2):11-30. doi: 10.1007/BF01870671.
本文引用的文献
1
Cs(+) causes a voltage-dependent block of inward K currents in resting skeletal muscle fibres.铯离子（Cs(+)）在静息骨骼肌纤维中引起内向钾电流的电压依赖性阻断。
Nature. 1977 May 12;267(5607):169-70. doi: 10.1038/267169a0.
2
Cation selective glass electrodes and their mode of operation.阳离子选择性玻璃电极及其工作模式。
Biophys J. 1962 Mar;2(2 Pt 2):259-323. doi: 10.1016/s0006-3495(62)86959-8.
3
Vagal and sympathetic effects on the pacemaker fibers in the sinus venosus of the heart.迷走神经和交感神经对心脏静脉窦起搏纤维的影响。
J Gen Physiol. 1956 May 20;39(5):715-33. doi: 10.1085/jgp.39.5.715.
4
Ion conductance and ion selectivity of potassium channels in snail neurones.蜗牛神经元中钾通道的离子电导和离子选择性
J Membr Biol. 1980 Dec 15;57(2):103-18. doi: 10.1007/BF01868997.
5
The permeability of endplate channels to monovalent and divalent metal cations.终板通道对单价和二价金属阳离子的通透性。
J Gen Physiol. 1980 May;75(5):493-510. doi: 10.1085/jgp.75.5.493.
6
The permeability of the endplate channel to organic cations in frog muscle.蛙肌终板通道对有机阳离子的通透性。
J Gen Physiol. 1980 May;75(5):469-92. doi: 10.1085/jgp.75.5.469.
7
Dynamic asymmetries in the squid axon membrane.
J Gen Physiol. 1968 May;51(5):Suppl:102S+.
8
Serotonin: two different inhibitory actions on snail neurons.
Science. 1971 Mar 26;171(3977):1252-4. doi: 10.1126/science.171.3977.1252.
9
Potassium channels in myelinated nerve. Selective permeability to small cations.有髓神经中的钾通道。对小阳离子的选择性通透性。
J Gen Physiol. 1973 Jun;61(6):669-86. doi: 10.1085/jgp.61.6.669.
10
Ionic selectivity of the sodium channel of frog skeletal muscle.蛙骨骼肌钠通道的离子选择性
J Gen Physiol. 1976 Mar;67(3):295-307. doi: 10.1085/jgp.67.3.295.
Zotero 插件