禽痘病毒感染对培养的鸡胚细胞脂质代谢的影响。
Effects of fowlpox virus infection on lipid metabolism in cultured chicken embryo cells.
作者信息
Buttke T M, Gafford L G
出版信息
J Virol. 1982 Aug;43(2):749-52. doi: 10.1128/JVI.43.2.749-752.1982.
Abstract
Lipid biosynthesis was measured in cultured chicken embryo cells after infection with fowlpox virus. Between 24 and 72 h postinfection, fowlpox virus-infected cells incorporated less [14C]acetate and 3H2O into fatty acids and sterols than did mock-infected cells, demonstrating a virus-dependent inhibition of general lipid metabolism. Two specific effects of fowlpox virus infection were an accumulation of C-4 alkylated sterol intermediates and inhibition of monounsaturated fatty acid biosynthesis.
摘要
在用禽痘病毒感染培养的鸡胚细胞后，对脂质生物合成进行了测定。在感染后24至72小时之间，感染禽痘病毒的细胞比模拟感染的细胞将更少的[14C]乙酸盐和3H2O掺入脂肪酸和固醇中，这表明存在病毒依赖性的一般脂质代谢抑制。禽痘病毒感染的两个特定效应是C-4烷基化固醇中间体的积累和单不饱和脂肪酸生物合成的抑制。
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2
Biochemical changes and incorporation of P32 in separated elements of the hyperplastic lesion of fowlpox.
Proc Soc Exp Biol Med. 1960 Dec;105:621-4. doi: 10.3181/00379727-105-26197.
3
Quantitative changes in lipid composition of tissues infected with fowlpox virus.
Proc Soc Exp Biol Med. 1958 May;98(1):65-7. doi: 10.3181/00379727-98-23942.
4
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J Biol Chem. 1957 Sep;228(1):255-62.
5
The effect of Theiler's GD VII virus on the intra-cellular distribution of radiophosphorus in mouse brain in vitro.
J Biol Chem. 1954 Sep;210(1):343-5.
6
20,25-Diazacholesterol, clofibric acid and 2,4-dichlorophenoxyacetic acid--all inducers of myotonia--perturb the post-lanosterol sector of sterol biosynthesis in cultured chick embryo fibroblasts.
Biochem Biophys Res Commun. 1980 Sep 16;96(1):34-8. doi: 10.1016/0006-291x(80)91177-8.
7
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