Hilker D M
Nutr Cancer. 1981;2(4):217-23. doi: 10.1080/01635588109513686.
Carcinogens naturally occurring in food include metabolites of microorganisms which infect plants during harvesting and storage; products of the normal metabolism of plants and products of chemical changes occurring during processing, preservation, preparation or which are picked up from the environment, including contaminated water or soil. Some examples of these types of carcinogens are: fungal metabolites such as aflatoxins in peanuts stored under improper conditions; safrol from the oil of various plants; tannin in tea, grain and grapes; and polycyclic hydrocarbons including benzo (a) pyrene formed by smoking meat and fish. Epidemiological studies indicate that there is a high incidence of gastric cancer in the areas of the world where smoked fish are common in diets. Vitamin A may play a role in preventing the carcinogenic action of polycyclic hydrocarbons.
食物中天然存在的致癌物包括在收获和储存期间感染植物的微生物的代谢产物;植物正常代谢的产物以及在加工、保存、制备过程中发生化学变化的产物,或从环境中摄取的产物,包括受污染的水或土壤。这类致癌物的一些例子有:储存条件不当的花生中的黄曲霉毒素等真菌代谢产物;各种植物油中的黄樟素;茶、谷物和葡萄中的单宁;以及包括熏制肉类和鱼类形成的苯并(a)芘在内的多环芳烃。流行病学研究表明,在饮食中常见熏鱼的世界地区,胃癌发病率很高。维生素A可能在预防多环芳烃的致癌作用中发挥作用。