Chauplannaz G, Bady B, Kopp N, Levrat R, Trillet M
Rev Neurol (Paris). 1982;138(3):249-51.
After voluntary inhalation of a domestic solvent containing N-Hexane and N-Heptane for three months, a 23-year-old woman developed motor deficit of the lower limbs, sensory symptoms and areflexia. Clinical disorders continued to progress after discontinuation of the intoxication, with a parallel aggravation of the E.M.G. disturbances. A nerve biopsy with ultrastructural study showed axon dilatation with accumulation of neurofilaments. The clinical, electrophysiological and pathological features of neuropathies induced by hexacarbon solvents are reviewed and their pathogenesis is discussed.
一名23岁女性在自愿吸入一种含有正己烷和正庚烷的家用溶剂三个月后，出现下肢运动功能障碍、感觉症状和反射消失。停止中毒后，临床症状持续进展，同时肌电图紊乱加重。神经活检及超微结构研究显示轴突扩张并伴有神经丝积聚。本文回顾了六碳溶剂所致神经病的临床、电生理和病理特征，并讨论了其发病机制。
