Imai S, Sekigawa S, Yamamoto H, Tsubura Y, Miyanaga M, Narita N, Mikami R
Acta Pathol Jpn. 1982 Jul;32(4):677-82. doi: 10.1111/j.1440-1827.1982.tb02069.x.
An autopsy case of bronchiolo-alveolar adenocarcinoma in the lung is reported. The patient is a 70-year-old male who complained of severe cough with 500-600 ml watery sputum a day, loss of weight. and general fatigue. Autopsy revealed numerous whitish tumors in various sizes with multiple cysts in both lungs, with no metastasis being found in any other organs. Histological findings identified the tumor as a bronchiolo-alveolar adenocarcinoma originating from the lungs. Electron-microscopic findings showed that the tumor cells were covered by prominent microvilli, and contained abundant irregularly-shaped cytoplasmic vacuoles suggestive of mucin.
报告了一例肺细支气管肺泡腺癌的尸检病例。患者为一名70岁男性,主诉严重咳嗽,每天咳出500 - 600毫升水样痰液,伴有体重减轻和全身乏力。尸检发现双肺有许多大小不一的白色肿瘤,伴有多个囊肿,未发现其他器官有转移。组织学检查结果确定该肿瘤为起源于肺的细支气管肺泡腺癌。电子显微镜检查结果显示,肿瘤细胞表面有明显的微绒毛,细胞质内含有大量不规则形状的空泡,提示为黏液。