Price J B, Schullinger J N, Santulli T V
Arch Surg. 1982 Sep;117(9):1139-41. doi: 10.1001/archsurg.1982.01380330007003.
In a consecutive series from 1968 to 1978, 11 hepatic resections encompassing at least two hepatic segments were carried out for neoplasia in pediatric patients varying in age from 7 days to 14 years. There were no operative deaths. These resections consisted of four right lobectomies, three extended right lobectomies, one right lobectomy with right nephrectomy and inferior vena caval resection, two left lobectomies, and one left extended lobectomy. Diagnoses were hepatoblastoma in six patients, Wilms' tumor invading the liver in two, hemangioendothelioma in two, and malignant mesenchymoma in one. Selective angiography and technetium Tc 99m sulfur colloid scintigraphy were important preoperative aids. Complications were infrequent and there were no major infections or biliary fistulas. There was one death eight months postoperatively due to recurrent hepatoblastoma. Vigorous hepatic regeneration occurred in all instances. Major hepatic resections are well tolerated in children and allow good subsequent development.
在1968年至1978年的一组连续病例中,对年龄从7天至14岁不等的小儿肿瘤患者进行了11例至少包括两个肝段的肝切除术。无手术死亡病例。这些切除术包括4例右半肝切除术、3例扩大右半肝切除术、1例右半肝切除术伴右肾及下腔静脉切除术、2例左半肝切除术和1例左扩大肝切除术。诊断结果为6例肝母细胞瘤、2例肾母细胞瘤侵犯肝脏、2例血管内皮瘤和1例恶性间叶瘤。选择性血管造影和锝Tc 99m硫胶体闪烁扫描是重要的术前辅助检查。并发症少见,无严重感染或胆瘘发生。术后8个月有1例因肝母细胞瘤复发死亡。所有病例均出现旺盛的肝再生。小儿对大肝切除术耐受性良好,术后发育良好。