Eisen A, Paty D, Hoirch M
Muscle Nerve. 1982 May-Jun;5(5):411-4. doi: 10.1002/mus.880050513.
Supernormality is a regular part of the recovery cycle of nerve. Supernormality was expressed in terms of amplitude, and in 20 control subjects the mean (S2 conditioned/S2 unconditioned) ratio of the median sensory nerve action potential amplitude recorded at the elbow measured 285 +/- 174 (range 119 to 783). A supramaximal conditioning shock was delivered 6 msec in advance of the test pulse. Seventeen (42.5%) of 40 patients with multiple sclerosis (MS) failed to demonstrate supernormality, the (S2 conditioned/S2 unconditioned) ratio being less than 100. This abnormality probably reflects a delay in recovery cycle and is additional evidence implicating peripheral nervous system involvement in multiple sclerosis.
超常期是神经恢复周期的正常组成部分。超常期通过振幅来表示，在20名对照受试者中，在肘部记录的正中感觉神经动作电位振幅的平均（条件刺激S2/非条件刺激S2）比值为285±174（范围为119至783）。在测试脉冲提前6毫秒施加超强条件刺激。40例多发性硬化症（MS）患者中有17例（42.5%）未表现出超常期，（条件刺激S2/非条件刺激S2）比值小于100。这种异常可能反映了恢复周期的延迟，是提示多发性硬化症累及周围神经系统的额外证据。
