Woll K H
Pflugers Arch. 1982 Jun;393(4):318-21. doi: 10.1007/BF00581417.
Voltage clamp experiments were performed on single myelinated nerve fibres of the frog Rana esculenta to study the influence of internally applied Ba on the potassium outward current IK. Potassium currents of Ba-treated fibres decay rapidly during 30 ms depolarizations of more than 60 mV. The time constant tau of decay and the steady state potassium current IKss are strongly voltage dependent. The equilibrium dissociation constant K of the Ba-receptor complex decreases e-fold for a 39 mV change of potential. The analysis suggests that the binding site is located at 30% of the membrane field seen from the inside of the axon.
对食用蛙（Rana esculenta）的单根有髓神经纤维进行电压钳实验，以研究细胞内施加钡对钾外向电流IK的影响。在超过60 mV的30 ms去极化过程中，经钡处理的纤维的钾电流迅速衰减。衰减的时间常数tau和稳态钾电流IKss强烈依赖于电压。钡 - 受体复合物的平衡解离常数K随着电位变化39 mV而呈指数下降。分析表明，结合位点位于从轴突内部观察到的膜电场的30%处。
