de Bruin G, Guy I, Van den Berg R J
Biophys J. 1984 Apr;45(4):855-8. doi: 10.1016/S0006-3495(84)84230-7.
The single K+-channel conductance was calculated from the variance of the spontaneous potassium noise currents in voltage clamped frog node. Essential for this calculation is the mean potassium conductance during the noise measurement. So far this quantity has been underestimated, apparently due to K+-ion accumulation. With the proper values, the single K+-channel conductance is an increasing function of membrane voltage.
通过电压钳制的青蛙神经节中自发钾离子噪声电流的方差来计算单个钾离子通道的电导。该计算的关键在于噪声测量期间的平均钾离子电导。到目前为止,这个量一直被低估,显然是由于钾离子积累所致。使用合适的值,单个钾离子通道的电导是膜电压的递增函数。