念珠菌性胆囊炎中酮康唑治疗失败的表象
Apparent ketoconazole failure in candidal cholecystitis.
作者信息
Brooks B J, Williams W L, Sanders C V, Marier R L
出版信息
Arch Intern Med. 1982 Oct;142(10):1934-5.
PMID:6289764
Abstract
Fungal acalculous cholecystitis is a rarely recognized complication of disseminated candidal infections. We report such a case of systemic candidiasis that developed in a man who was diabetic while he was receiving broad-spectrum antibiotic therapy for an infected foot ulcer. Ketoconazole, a new imidazole antifungal agent, was used successfully to treat the systemic candidal infection but it failed to eradicate the fungus in the biliary tract.
摘要
真菌性无结石性胆囊炎是播散性念珠菌感染一种罕见的并发症。我们报告了这样一例系统性念珠菌病病例，该病例发生在一名患有糖尿病的男性身上，当时他因足部感染性溃疡正在接受广谱抗生素治疗。酮康唑，一种新型咪唑类抗真菌药，成功用于治疗系统性念珠菌感染，但未能根除胆道中的真菌。
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Apparent ketoconazole failure in candidal cholecystitis.念珠菌性胆囊炎中酮康唑治疗失败的表象
Arch Intern Med. 1982 Oct;142(10):1934-5.
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引用本文的文献
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Choledochal fungal ball. An unusual cause of biliary obstruction.胆管真菌球。一种罕见的胆道梗阻原因。
Dig Dis Sci. 1988 Aug;33(8):1030-4. doi: 10.1007/BF01536002.
2
Clinical pharmacokinetics of ketoconazole.酮康唑的临床药代动力学
Clin Pharmacokinet. 1988 Jan;14(1):13-34. doi: 10.2165/00003088-198814010-00002.
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