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[Lipid peroxidation and the myeloperoxidase activity of neutrophilic leukocytes in shereshevskyĭ-Turner syndrome].

作者信息

Davidenkova E F, Grigor'eva V V, Shafran M G, Verlinskaia D K, Prozorova M V

出版信息

Biull Eksp Biol Med. 1982 Aug;94(8):72-3.

PMID:6289937
Abstract

The level of lipid peroxides, activity and thermostability of myeloperoxidase have been studied in neutrophil extracts from the peripheral blood of patients with the Shereshevsky-Turner syndrome and in normal subjects. A statistically significant rise in the level of lipid peroxides and respective decrease in the activity and thermostability of myeloperoxidase have been revealed in the patients as compared with the control group. These findings point to functional inferiority of neutrophils. It is probable that at the basis of the disorders seen there lie an abnormal set of sex chromosomes and upset hormonal regulation determined by the abnormality.

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