血清对人类癌症中髓过氧化物酶的抑制作用。
Serum inhibitory effect on myeloperoxidase in human cancer.
作者信息
Senelar B, Michel R, Tournamille J, Vannereau H, Escola M J, Taib J, Craste de Paulet A
出版信息
Br J Exp Pathol. 1982 Jun;63(3):320-4.
The myeloperoxidase level is strongly depressed in leucocytes from cancer patients (-59%). Moreover sera of the same subjects induce a significant decrease in the myeloperoxidase activity of healthy subjects' leucocytes (-43%). We have found no convincing evidence of any correlation between the level of the inhibitory effect of sera and the tumour type. The fact that sera from cancer patients interfere with neutrophil responses in this way does not exclude the possibility that abnormal cellular functions were also operative.
癌症患者白细胞中的髓过氧化物酶水平显著降低（-59%）。此外，这些患者的血清可使健康受试者白细胞的髓过氧化物酶活性显著下降（-43%）。我们没有发现血清抑制作用水平与肿瘤类型之间存在任何相关性的令人信服的证据。癌症患者的血清以这种方式干扰中性粒细胞反应这一事实并不排除异常细胞功能也起作用的可能性。
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