Varga T, Szabó A
Z Rechtsmed. 1978 Jan 31;80(4):311-8. doi: 10.1007/BF02092329.
Myocardial lesions occuring in diseases with acute increase of intracranial pressure were investigated. Morphologic alterations in heart muscle in spite of different lengh of surviving and various causes of the death were of similar type. In every case subendocardial haemorrhage could be observed on the septal surface and on the papillary muscle of the left ventricle. Focal intracellular edema, myocytolysis were revealed in 76%, focal necrosis of hypercontractic type developed in 52% of the cases. Cellular infiltration occurred around the alternations observed in 3 cases. It is concluded, that damage to the heart muscle is not caused directly by the increased intracranial pressure or catecholamine mobilisation, but seems to be the consequence of the acute myocardial hypoxia.
对颅内压急性升高疾病中发生的心肌病变进行了研究。尽管存活时间不同且死亡原因各异，但心肌的形态学改变类型相似。在每一病例中，均可在左心室间隔面和乳头肌上观察到心内膜下出血。76%的病例出现局灶性细胞内水肿、肌细胞溶解，52%的病例发生高收缩型局灶性坏死。在3例观察到的病变周围出现细胞浸润。得出的结论是，心肌损伤并非由颅内压升高或儿茶酚胺动员直接引起，而似乎是急性心肌缺氧的后果。
