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A transient outward current in rat sympathetic neurones.

作者信息

Galvan M

出版信息

Neurosci Lett. 1982 Aug 31;31(3):295-300. doi: 10.1016/0304-3940(82)90036-2.

DOI:10.1016/0304-3940(82)90036-2
PMID:6290949
Abstract

Voltage-clamped rat sympathetic neurones exhibited a transient outward current similar to that previously described in invertebrate neurones and marine egg cells. It had an activation threshold of about -60 mV and displayed both voltage and time-dependent inactivation. In current clamp, this current manifested as a pronounced outward rectification at the onset of electrotonic potentials, increasing the latency to directly-evoked action potentials. The amplitude of the current was dependent on the external K+ concentration and was reduced by 4-aminopyridine.

摘要

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