Sauer H, Drings P, Schalhorn A, Wilmanns W
Onkologie. 1982 Aug;5(4):174-7. doi: 10.1159/000214995.
5 patients with small-cell lung cancer were treated with high-dose methotrexate (1.75-16 g). No significant tumor reduction could be demonstrated. High-dose methotrexate therapy cannot be recommended for the treatment of small-cell lung cancer. Other established and successful regimens are available.
5例小细胞肺癌患者接受了高剂量甲氨蝶呤（1.75 - 16克）治疗。未显示出明显的肿瘤缩小。不推荐高剂量甲氨蝶呤疗法用于治疗小细胞肺癌。有其他已确立且成功的治疗方案可供选择。
