Thomas J L, Bernardino M E, Vermess M, Barnes P A, Fuller L M, Hagemeister F B, Doppman J, Fisher R I, Longo D L
Radiology. 1982 Dec;145(3):629-34. doi: 10.1148/radiology.145.3.6292995.
Thirty-nine patients with lymphoma were evaluated prospectively to determine the usefulness of Ethiodol-Oil-Emulsion-13 (EOE-13) in the detection of hepatosplenic lymphoma by computed tomography. The detection rate in the spleen increased from 8% (before EOE-13 infusion) to 92% (after EOE-13 infusion). In ten of 39 patients (25%) in this series, lymphomatous disease was recognized only on the postinfusion computed tomographic scan. The postinfusion EOE-13 study demonstrated additional visceral abnormalities in 38% of the patients. The potential usefulness, limitations, and toxicity of this hepatosplenic-specific imaging agent are discussed.
对39例淋巴瘤患者进行前瞻性评估,以确定乙碘油乳剂-13(EOE-13)在计算机断层扫描检测肝脾淋巴瘤中的效用。脾脏的检测率从(注入EOE-13前的)8%提高到了(注入EOE-13后的)92%。在该系列的39例患者中有10例(25%),仅在注入后计算机断层扫描中发现淋巴瘤疾病。注入EOE-13后的研究显示,38%的患者有额外的内脏异常。本文讨论了这种肝脾特异性显像剂的潜在效用、局限性和毒性。