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Copy number mutations (Cop-) of the plasmid containing the replication origin (oriC) of the Escherichia coli chromosome: lethal effect of the cop region cloned onto a high-copy-number vector on host cells.

作者信息

Yamaguchi K, Yamaguchi M

出版信息

J Bacteriol. 1983 Jan;153(1):550-4. doi: 10.1128/jb.153.1.550-554.1983.

DOI:10.1128/jb.153.1.550-554.1983
PMID:6294061
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC217408/
Abstract

High-copy-number mutants were isolated from an oriC plasmid. They carried insertion mutations within a region (about 470 base pairs) near the uncB gene. When a segment containing this region was cloned onto a high-copy-number plasmid, such a plasmid could be maintained as an intact form only when it was present in a lower copy number.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/217408/d73d674d83fc/jbacter00248-0575-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/217408/00af3e09e661/jbacter00248-0574-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/217408/d73d674d83fc/jbacter00248-0575-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/217408/00af3e09e661/jbacter00248-0574-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/217408/d73d674d83fc/jbacter00248-0575-a.jpg

相似文献

1
Copy number mutations (Cop-) of the plasmid containing the replication origin (oriC) of the Escherichia coli chromosome: lethal effect of the cop region cloned onto a high-copy-number vector on host cells.
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引用本文的文献

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Mol Gen Genet. 1984;194(1-2):179-87. doi: 10.1007/BF00383514.
2
Overproduction of subunit a of the F0 component of proton-translocating ATPase inhibits growth of Escherichia coli cells.质子转运ATP酶F0组分的亚基a过量产生会抑制大肠杆菌细胞的生长。
J Bacteriol. 1984 Apr;158(1):300-6. doi: 10.1128/jb.158.1.300-306.1984.
3
Cloning and expression of uncI, the first gene of the unc operon of Escherichia coli.

本文引用的文献

1
Copy-number mutants of the plasmid carrying the replication origin of the Escherichia coli chromosome: evidence for a control region of replication.携带大肠杆菌染色体复制起点的质粒的拷贝数突变体：复制控制区的证据。
Proc Natl Acad Sci U S A. 1980 Jul;77(7):3993-7. doi: 10.1073/pnas.77.7.3993.
2
Establishment of Escherichia coli cells with an integrated high copy number plasmid.构建携带整合型高拷贝质粒的大肠杆菌细胞。
Mol Gen Genet. 1980;178(3):525-33. doi: 10.1007/BF00337857.
3
Three genes coding for subunits of the membrane sector (F0) of the Escherichia coli adenosine triphosphatase complex.
大肠杆菌unc操纵子首个基因uncI的克隆与表达
J Bacteriol. 1983 Sep;155(3):1265-70. doi: 10.1128/jb.155.3.1265-1270.1983.
4
Proton conduction by subunit a of the membrane-bound ATP synthase of Escherichia coli revealed after induced overproduction.大肠杆菌膜结合ATP合酶亚基a在诱导过量表达后显示出质子传导作用。
EMBO J. 1985 Sep;4(9):2357-63. doi: 10.1002/j.1460-2075.1985.tb03939.x.
编码大肠杆菌三磷酸腺苷酶复合体膜部（F0）亚基的三个基因。
J Bacteriol. 1981 Jan;145(1):200-10. doi: 10.1128/jb.145.1.200-210.1981.
4
Incompatibility of plasmids containing the replication origin of the Escherichia coli chromosome.含有大肠杆菌染色体复制起点的质粒的不相容性。
Proc Natl Acad Sci U S A. 1982 Sep;79(17):5347-51. doi: 10.1073/pnas.79.17.5347.
5
Nucleotide sequence of the genes for F0 components of the proton-translocating ATPase from Escherichia coli: prediction of the primary structure of F0 subunits.大肠杆菌质子转运ATP酶F0组分基因的核苷酸序列：F0亚基一级结构的预测
Biochem Biophys Res Commun. 1981 Nov 30;103(2):613-20. doi: 10.1016/0006-291x(81)90495-2.
6
The atp operon: nucleotide sequence of the promoter and the genes for the membrane proteins, and the delta subunit of Escherichia coli ATP-synthase.ATP操纵子：大肠杆菌ATP合酶膜蛋白及δ亚基基因启动子的核苷酸序列
Nucleic Acids Res. 1981 Aug 25;9(16):3919-26. doi: 10.1093/nar/9.16.3919.
7
Plasmid ColE1 incompatibility determined by interaction of RNA I with primer transcript.由RNA I与引物转录本相互作用决定的质粒ColE1不相容性。
Proc Natl Acad Sci U S A. 1981 Oct;78(10):6096-100. doi: 10.1073/pnas.78.10.6096.
8
Studies on radiation-sensitive mutants of E. coli. II. Breakage and repair of ultraviolet irradiated intracellular DNA of phage lambda.大肠杆菌辐射敏感突变体的研究。II. 噬菌体λ紫外线照射后细胞内DNA的断裂与修复
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Plasmids carrying oriC can integrate at or near the chromosome origin of Escherichia coli in the absence of a functional recA product.
Cold Spring Harb Symp Quant Biol. 1979;43 Pt 2:1069-72. doi: 10.1101/sqb.1979.043.01.118.