Clinical experience with cefotaxime in the treatment of patients with bacteremia.

Seventy-three of 129 patients with bacteremia were observed for their responses to cefotaxime therapy. The clinical response to treatment with cefotaxime was satisfactory in 68 (93%) of the 73 patients. The bacteriologic response was satisfactory in 64 (92.7%) of the 69 patients with bacteriologic evidence of bacteremia. One hundred twenty-nine patients were observed for adverse reactions. Four patients had adverse reactions serious enough to warrant discontinuation of therapy, and three patients developed superinfections.