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[肾脏水平磷和钙代谢的激素调节]

[Hormonal regulation of phosphorus and calcium metabolism at the kidney level].

作者信息

Bourgoignie J J

出版信息

Schweiz Med Wochenschr. 1982 Dec 4;112(49):1759-63.

PMID:6294822
Abstract

The effects of hormones in the renal handling of calcium and phosphate are reviewed in the context of transport events occurring in different segments of the nephron. Hormones that influence the renal handling of calcium include parathyroid hormone, calcitonin and vitamin D. However, the kidney plays only a minor role in the maintenance of calcium balance. Hormones that modify the renal handling of phosphate are parathyroid hormone, thyroid hormone, growth hormone, glucocorticoids and vitamin D. In contrast to calcium, the kidney plays an important role in the maintenance of phosphate balance. In this endocrine context the contribution of the kidney is reviewed in clinical conditions of hypo- and hyperphosphatemia.

摘要

本文在肾单位不同节段发生的转运过程的背景下,综述了激素对肾脏处理钙和磷的影响。影响肾脏处理钙的激素包括甲状旁腺激素、降钙素和维生素D。然而,肾脏在维持钙平衡方面仅起次要作用。调节肾脏处理磷的激素有甲状旁腺激素、甲状腺激素、生长激素、糖皮质激素和维生素D。与钙不同,肾脏在维持磷平衡方面起着重要作用。在这种内分泌背景下,本文综述了低磷血症和高磷血症临床情况下肾脏的作用。

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