Sontheimer R D, Garibaldi R A, Krueger G G
Arch Dermatol. 1978 Feb;114(2):241-4.
The Stevens-Johnson syndrome is a multisystem inflammatory disorder associated with a widespread erythematous eruption that can result in death. Although usually considered a pediatric disease, this syndrome frequently affects adults. There are many etiologic associations including drugs and infections; however, the pathophysiology of the syndrome remains obscure. Treatment at present is symptomatic and supportive. Although frequently used, the beneficial role of corticosteroids in this syndrome remains to be proved. The case report describes a young woman who after treatment with several drugs developed the Stevens-Johnson syndrome in association with a Mycoplasma pneumoniae infection. We include a brief review of the literature with emphasis on the Stevens-Johnsons syndrome's association with M pneumoniae infections. Those caring for patients with skin disease should be aware of the association between such treatable infections and this syndrome.
史蒂文斯-约翰逊综合征是一种多系统炎症性疾病，伴有广泛的红斑疹，可导致死亡。虽然通常被认为是一种儿科疾病，但该综合征也常影响成年人。病因有多种，包括药物和感染；然而，该综合征的病理生理学仍不清楚。目前的治疗是对症和支持性的。尽管皮质类固醇经常被使用，但其在该综合征中的有益作用仍有待证实。该病例报告描述了一名年轻女性，在使用多种药物治疗后，与肺炎支原体感染相关联地患上了史蒂文斯-约翰逊综合征。我们简要回顾了文献，重点是史蒂文斯-约翰逊综合征与肺炎支原体感染的关联。护理皮肤病患者的人员应了解这种可治疗感染与该综合征之间的关联。
