Rasmussen J E, Ahmed A R
Arch Dermatol. 1978 Mar;114(3):371-2.
Of 52 patients with proved Trichophyton tonsurans infection of the scalp, 16 had an inflammatory reaction to this infection (kerion), while the rest had only slight scaling and broken hairs (black dot ring-worm). Each patient was tested with trichophytin antigen to determine whether cell-mediated immunity (CMI) was responsible for the differences in these different clinical presentations. Fifteen of 16 with kerion had a 48-hour reaction greater than 10 mm, while none of the 36 with noninflammatory (black dot) tinea capitis had a similar response. This suggests that the patient's immune response (CMI) may be responsible for kerion infections of the scalp and that therapy could be directed initially toward suppressing this reaction.
在52例已证实头皮感染断发毛癣菌的患者中，16例对此感染有炎症反应（脓癣），其余患者仅有轻微脱屑和断发（黑点癣）。对每位患者进行癣菌素抗原检测，以确定细胞介导免疫（CMI）是否与这些不同临床表现的差异有关。16例脓癣患者中有15例48小时反应大于10毫米，而36例非炎症性（黑点）头癣患者均无类似反应。这表明患者的免疫反应（CMI）可能与头皮脓癣感染有关，并且治疗可首先针对抑制这种反应。
