Agamova K A, Kadirov A M, Krylova G P
Arkh Patol. 1978;40(1):60-5.
Parallel cytological and histological studies were performed for 87 patients with pulmonary adenocarcinoma. Sputum, impression smears of the bronchial mucosa, aspirates from the bronchi, punctates of the tumor obtained transbronchially, pieces of tumor obtained at bronchoscopy, and operation material were examined. Considerable difficulties wre found in cytological diagnosis of adenocarcinomas due to degenerative changes in tumor cells, the presence of cells of the metaplastic columnar epithelium and marked anaplasia of tumor cells in adenocarcinoma with low differentiation. The frequency of diagnostic errors was 20.0--50.6% depending on the histological form of adenocarcinoma and the accompanying processes in bronchi. The cytological criteria improving the differential diagnosis of adenocarcinoma are presented. The validity of cytological diagnosis of adenocarcinoma does not depend on the nature of the material examined.
对87例肺腺癌患者进行了细胞学和组织学平行研究。检查了痰液、支气管黏膜印片、支气管吸出物、经支气管获取的肿瘤穿刺物、支气管镜检查时获取的肿瘤组织块以及手术材料。由于肿瘤细胞的退行性变、化生柱状上皮细胞的存在以及低分化腺癌中肿瘤细胞的明显间变，腺癌的细胞学诊断存在相当大的困难。根据腺癌的组织学类型和支气管伴随病变的不同，诊断错误的发生率为20.0%至50.6%。文中提出了有助于腺癌鉴别诊断的细胞学标准。腺癌细胞学诊断的有效性并不取决于所检查材料的性质。
